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Infamous E Liquid is owned and operated by Jimmy and Leigh Anne Dargocey. Jimmy started vaping in 2012 after Leigh Anne was diagnosed with thyroid cancer. After trying and failing various other ways to quit smoking, he finally discovered vaping as an effective way for him to quit. Soon after, he delved into DIY using his culinary background and created his own E liquids. Friends and other E Liquid manufacturers encouraged Jimmy to start his own line, and Infamous E Liquid was born in 2014. The original Infamous E Liquid line is now joined by new lines The Fallen, Doughy O's, Lowbrow and In House.

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